Uterine fibroids are noncancerous growths that develop within or on the uterus, most commonly during a woman's reproductive years. Also known as leiomyomas or myomas, fibroids are not linked to an increased risk of uterine cancer and rarely become cancerous.
Fibroids can vary greatly in size, ranging from tiny growths that are invisible to the naked eye to large masses that can enlarge and distort the uterus. Some women develop a single fibroid, while others may have multiple fibroids.
Many women experience uterine fibroids without any noticeable symptoms. They are often discovered during a routine pelvic examination or prenatal ultrasound. When symptoms do occur, early diagnosis and appropriate treatment can help relieve discomfort and improve quality of life.
Many women with uterine fibroids experience no symptoms. However, when symptoms occur, they usually depend on the size, number, and location of the fibroids.
Excessive menstrual bleeding that may interfere with daily life.
Menstrual periods lasting longer than one week.
Persistent discomfort, pressure, or pain in the pelvic region.
Pressure on the bladder causing the need to urinate more often.
Fibroids may press against the bladder, making urination difficult.
Large fibroids can put pressure on the bowel, causing constipation.
Fibroids may press on nearby nerves, leading to pain in the back or legs.
Rarely, a fibroid may outgrow its blood supply, causing acute pain.
Fibroids may be intramural, submucosal, or subserosal depending on where they develop.
Although many uterine fibroids do not cause symptoms, you should consult your doctor if you experience persistent discomfort, abnormal bleeding, or other concerning symptoms.
Consult your gynecologist if you notice these symptoms
Do not delay treatment if you experience these conditions
The exact cause of uterine fibroids is not fully understood. However, research suggests that genetic, hormonal, and biological factors play an important role in their development and growth.
Many fibroids contain genetic changes that differ from normal uterine muscle cells.
Estrogen and progesterone encourage fibroid growth by stimulating uterine tissue.
Fibroids contain more estrogen and progesterone receptors than normal uterine muscle.
Natural substances such as insulin-like growth factor may contribute to fibroid development.
Increased ECM makes fibroids firm and supports their growth by storing growth factors.
Fibroids are believed to develop from a single stem cell in the uterine muscle (myometrium).
Fibroids may grow slowly, rapidly, remain unchanged, or shrink naturally, especially after menopause.
Find answers to common questions about uterine fibroids, their symptoms, causes, diagnosis, treatment options, and when to seek medical care.